New Publication: Diffusible iodine-based contrast-enhanced computed tomography (diceCT)—an emerging tool for rapid, high-resolution, 3-D imaging of metazoan soft tissues


diceCT eclectus parrot head
Cover: An eclectus parrot (Eclectus roratus) stained by C. M. Holliday (University of Missouri) and micro-CT scanned by L. M. Witmer (Ohio University) according to the diceCT protocol presented by Gignac et al. (pp. 889–909) that reveals unprecedented soft-tissue detail in CT scanned specimens.

“Use of iodine as a contrast agent for computed tomography visualizations has been a growing area of research for the last several years. In this open access study we provide a summary of the diceCT literature and synthesize the elements of successful approaches: we analyze factors that govern success at each step of the diceCT imaging pipeline; we recommend a standard for reporting details of specimen preparation, storage, and imaging that will be pivotal to the repeatability and broader adoption of diceCT going forward; and we discuss cutting-edge applications and future directions for diceCT techniques. We anticipate robust growth within the diceCT community and the realization of new horizons in contrast-enhanced imaging—and it is our explicit purpose to spur the adoption of this relatively nascent approach by the morphology community as a whole.”

–Lead Author Paul Gignac

Access the paper in the Journal of Anatomy!